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mt-Nd2(a) Modifies Resistance Against Autoimmune Type 1 Diabetes in NOD Mice at the Level of the Pancreatic β-Cell

OBJECTIVE: To investigate whether a single nucleotide polymorphism (SNP) in the mitochondrial gene for NADH dehydrogenase 2 (mt-Nd2) can modulate susceptibility to type 1 diabetes in NOD mice. RESEARCH DESIGN AND METHODS: NOD/ShiLtJ mice conplastic for the alloxan resistant (ALR)/Lt-derived mt-Nd2(a...

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Detalles Bibliográficos
Autores principales:	Chen, Jing, Gusdon, Aaron M., Piganelli, Jon, Leiter, Edward H., Mathews, Clayton E.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012193/ https://www.ncbi.nlm.nih.gov/pubmed/20980458 http://dx.doi.org/10.2337/db10-1241

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