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Regulation by phosphodiesterase isoforms of protein kinase A-mediated attenuation of myocardial protein kinase D activation

Protein kinase D (PKD) targets several proteins in the heart, including cardiac troponin I (cTnI) and class II histone deacetylases, and regulates cardiac contraction and hypertrophy. In adult rat ventricular myocytes (ARVM), PKD activation by endothelin-1 (ET1) occurs via protein kinase Cε and is a...

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Detalles Bibliográficos
Autores principales:	Haworth, Robert S., Cuello, Friederike, Avkiran, Metin
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Original Contribution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012212/ https://www.ncbi.nlm.nih.gov/pubmed/20725733 http://dx.doi.org/10.1007/s00395-010-0116-1

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