EFFECT OF LITHIUM CARBONATE ON RENAL AND EXTRA-RENAL FUNCTIONS OF RATS

Effect of high doses of lithium carbonate (40 rag/Kg.i.p. and p.o.) and lithium chloride (40 mg/Kg.i.p.) on renal and extra-renal functions were studied in normal male Charles Foster Strain of rats. Insignificant effect on urine output, creatinine clerance, sodium, potassium and lithium excretion wa...

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Detalles Bibliográficos
Autor principal: Puri, V.N.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1984
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012255/
https://www.ncbi.nlm.nih.gov/pubmed/21965958
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author Puri, V.N.
author_facet Puri, V.N.
author_sort Puri, V.N.
collection PubMed
description Effect of high doses of lithium carbonate (40 rag/Kg.i.p. and p.o.) and lithium chloride (40 mg/Kg.i.p.) on renal and extra-renal functions were studied in normal male Charles Foster Strain of rats. Insignificant effect on urine output, creatinine clerance, sodium, potassium and lithium excretion was observed with these salts. Antidiuretic hormone levels were also not effected. However lithium clearance was significantly raised in both groups with lithium carbonate and with lithium chloride treated rats. Lithium carbonate and lithium chloride had failed to produce nephrogenic polyuric syndrome in this strain of rats.
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spelling pubmed-30122552011-10-02 EFFECT OF LITHIUM CARBONATE ON RENAL AND EXTRA-RENAL FUNCTIONS OF RATS Puri, V.N. Indian J Psychiatry Original Article Effect of high doses of lithium carbonate (40 rag/Kg.i.p. and p.o.) and lithium chloride (40 mg/Kg.i.p.) on renal and extra-renal functions were studied in normal male Charles Foster Strain of rats. Insignificant effect on urine output, creatinine clerance, sodium, potassium and lithium excretion was observed with these salts. Antidiuretic hormone levels were also not effected. However lithium clearance was significantly raised in both groups with lithium carbonate and with lithium chloride treated rats. Lithium carbonate and lithium chloride had failed to produce nephrogenic polyuric syndrome in this strain of rats. Medknow Publications 1984 /pmc/articles/PMC3012255/ /pubmed/21965958 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Puri, V.N.
EFFECT OF LITHIUM CARBONATE ON RENAL AND EXTRA-RENAL FUNCTIONS OF RATS
title EFFECT OF LITHIUM CARBONATE ON RENAL AND EXTRA-RENAL FUNCTIONS OF RATS
title_full EFFECT OF LITHIUM CARBONATE ON RENAL AND EXTRA-RENAL FUNCTIONS OF RATS
title_fullStr EFFECT OF LITHIUM CARBONATE ON RENAL AND EXTRA-RENAL FUNCTIONS OF RATS
title_full_unstemmed EFFECT OF LITHIUM CARBONATE ON RENAL AND EXTRA-RENAL FUNCTIONS OF RATS
title_short EFFECT OF LITHIUM CARBONATE ON RENAL AND EXTRA-RENAL FUNCTIONS OF RATS
title_sort effect of lithium carbonate on renal and extra-renal functions of rats
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012255/
https://www.ncbi.nlm.nih.gov/pubmed/21965958
work_keys_str_mv AT purivn effectoflithiumcarbonateonrenalandextrarenalfunctionsofrats

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