Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-α2b treatment

A 7-year-old boy presented with hematochezia and abdominal pain. A 3.7-cm-sized mass was identified in the ascending colon by abdominal computed tomography and colonoscopy. The patient underwent surgical resection. Pathological examination revealed a low-grade perivascular epithelioid cell tumor (PE...

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Autores principales: Park, Sun Ju, Han, Dong Kyun, Baek, Hee Jo, Chung, Sang Young, Nam, Jong Hee, Kook, Hoon, Hwang, Tai Ju
Formato: Texto
Lenguaje:English
Publicado: The Korean Pediatric Society 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012279/
https://www.ncbi.nlm.nih.gov/pubmed/21218021
http://dx.doi.org/10.3345/kjp.2010.53.11.975
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author Park, Sun Ju
Han, Dong Kyun
Baek, Hee Jo
Chung, Sang Young
Nam, Jong Hee
Kook, Hoon
Hwang, Tai Ju
author_facet Park, Sun Ju
Han, Dong Kyun
Baek, Hee Jo
Chung, Sang Young
Nam, Jong Hee
Kook, Hoon
Hwang, Tai Ju
author_sort Park, Sun Ju
collection PubMed
description A 7-year-old boy presented with hematochezia and abdominal pain. A 3.7-cm-sized mass was identified in the ascending colon by abdominal computed tomography and colonoscopy. The patient underwent surgical resection. Pathological examination revealed a low-grade perivascular epithelioid cell tumor (PEComa). PEComa in the colon is very rare. Only a few cases have been reported so far. An effective treatment method for this rare tumor has not been established yet. The patient received adjuvant interferon-α immunotherapy for 1 year. He has been tumor-free for 26 months since the initial diagnosis. This report is the first documented case of the use of interferon-α for pediatric PEComa of the colon.
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spelling pubmed-30122792011-01-07 Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-α2b treatment Park, Sun Ju Han, Dong Kyun Baek, Hee Jo Chung, Sang Young Nam, Jong Hee Kook, Hoon Hwang, Tai Ju Korean J Pediatr Case Report A 7-year-old boy presented with hematochezia and abdominal pain. A 3.7-cm-sized mass was identified in the ascending colon by abdominal computed tomography and colonoscopy. The patient underwent surgical resection. Pathological examination revealed a low-grade perivascular epithelioid cell tumor (PEComa). PEComa in the colon is very rare. Only a few cases have been reported so far. An effective treatment method for this rare tumor has not been established yet. The patient received adjuvant interferon-α immunotherapy for 1 year. He has been tumor-free for 26 months since the initial diagnosis. This report is the first documented case of the use of interferon-α for pediatric PEComa of the colon. The Korean Pediatric Society 2010-11 2010-11-30 /pmc/articles/PMC3012279/ /pubmed/21218021 http://dx.doi.org/10.3345/kjp.2010.53.11.975 Text en Copyright © 2010 by The Korean Pediatric Society http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Park, Sun Ju
Han, Dong Kyun
Baek, Hee Jo
Chung, Sang Young
Nam, Jong Hee
Kook, Hoon
Hwang, Tai Ju
Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-α2b treatment
title Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-α2b treatment
title_full Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-α2b treatment
title_fullStr Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-α2b treatment
title_full_unstemmed Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-α2b treatment
title_short Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-α2b treatment
title_sort perivascular epithelioid cell tumor (pecoma) of the ascending colon: the implication of ifn-α2b treatment
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012279/
https://www.ncbi.nlm.nih.gov/pubmed/21218021
http://dx.doi.org/10.3345/kjp.2010.53.11.975
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