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DRUG SURVEILLANCE PROGRAMME IN PSYCHIATRY - ADVERSE DURG REACTIONS

In a clinically monitored surveillance of adverse drug reactions in a sample of 186 indoor patients in a general hospital over an average hospital stay of about two weeks, the following points were noteworthy. 32.8% of the patients reported side-effects and of these 79.3% were of mild to moderate in...

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Detalles Bibliográficos
Autores principales: Shah, L.P., Ayyar, K.S., Agarawal, B.R., Pradhan, P.V., Bagadia, V.N., Gupta, K.C., Paul, T., Santhanam, H., Sheth, U.K.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1983
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012325/
https://www.ncbi.nlm.nih.gov/pubmed/21847294
Descripción
Sumario:In a clinically monitored surveillance of adverse drug reactions in a sample of 186 indoor patients in a general hospital over an average hospital stay of about two weeks, the following points were noteworthy. 32.8% of the patients reported side-effects and of these 79.3% were of mild to moderate intensity. Side-effects could be easily managed by specific antidotes and reassurance and permitted continuation of the same medication. There was no association between side-effects and socio-demography or clinical characteristics of the patient. Side-effects fitted in with the pharmacological profiles of the drugs used. In only 7.3% of cases was major treatment change made after the occurrence of the side effect. Improvement was independent of side-effects and no unusual or toxic reactions were seen.