EFFECTS OF LONG-TERM LITHIUM CARBONATE TREATMENT ON THYROID FUNCTION IN PSYCHIATRIC PATIENTS

The effect of long-term lithium carbonate treatment on thyroid function was investigated in 40 clinically euthyroid patients with Manic Depressive Psychosis. Before lithium treatment, all patients showed normal levels (T(4)) of serum total thyroxine, free thyroxine index and thyrotropin (TSH). After...

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Detalles Bibliográficos
Autores principales: Kuruvilla, K., Karunanidhi, A., Kanagasabapathy, A.S.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1983
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012349/
https://www.ncbi.nlm.nih.gov/pubmed/21847264
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author Kuruvilla, K.
Karunanidhi, A.
Kanagasabapathy, A.S.
author_facet Kuruvilla, K.
Karunanidhi, A.
Kanagasabapathy, A.S.
author_sort Kuruvilla, K.
collection PubMed
description The effect of long-term lithium carbonate treatment on thyroid function was investigated in 40 clinically euthyroid patients with Manic Depressive Psychosis. Before lithium treatment, all patients showed normal levels (T(4)) of serum total thyroxine, free thyroxine index and thyrotropin (TSH). After lithium carbonate treatment for a mean period of 24 months, these patients did not show any significant change in the mean values of serum total T(4), free thyroxine index and TSH. None showed clinical symptoms of goitre and hypothyroidism after long-term lithium treatment. It is concluded that lithium therapy in euthyroid psychiatric patients has no adverse effect on thyroid function and en the pituitary secretion of TSH.
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spelling pubmed-30123492011-08-16 EFFECTS OF LONG-TERM LITHIUM CARBONATE TREATMENT ON THYROID FUNCTION IN PSYCHIATRIC PATIENTS Kuruvilla, K. Karunanidhi, A. Kanagasabapathy, A.S. Indian J Psychiatry Original Article The effect of long-term lithium carbonate treatment on thyroid function was investigated in 40 clinically euthyroid patients with Manic Depressive Psychosis. Before lithium treatment, all patients showed normal levels (T(4)) of serum total thyroxine, free thyroxine index and thyrotropin (TSH). After lithium carbonate treatment for a mean period of 24 months, these patients did not show any significant change in the mean values of serum total T(4), free thyroxine index and TSH. None showed clinical symptoms of goitre and hypothyroidism after long-term lithium treatment. It is concluded that lithium therapy in euthyroid psychiatric patients has no adverse effect on thyroid function and en the pituitary secretion of TSH. Medknow Publications 1983 /pmc/articles/PMC3012349/ /pubmed/21847264 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kuruvilla, K.
Karunanidhi, A.
Kanagasabapathy, A.S.
EFFECTS OF LONG-TERM LITHIUM CARBONATE TREATMENT ON THYROID FUNCTION IN PSYCHIATRIC PATIENTS
title EFFECTS OF LONG-TERM LITHIUM CARBONATE TREATMENT ON THYROID FUNCTION IN PSYCHIATRIC PATIENTS
title_full EFFECTS OF LONG-TERM LITHIUM CARBONATE TREATMENT ON THYROID FUNCTION IN PSYCHIATRIC PATIENTS
title_fullStr EFFECTS OF LONG-TERM LITHIUM CARBONATE TREATMENT ON THYROID FUNCTION IN PSYCHIATRIC PATIENTS
title_full_unstemmed EFFECTS OF LONG-TERM LITHIUM CARBONATE TREATMENT ON THYROID FUNCTION IN PSYCHIATRIC PATIENTS
title_short EFFECTS OF LONG-TERM LITHIUM CARBONATE TREATMENT ON THYROID FUNCTION IN PSYCHIATRIC PATIENTS
title_sort effects of long-term lithium carbonate treatment on thyroid function in psychiatric patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012349/
https://www.ncbi.nlm.nih.gov/pubmed/21847264
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