Mimotopes selected with a neutralizing antibody against urease B from Helicobacter pylori induce enzyme inhibitory antibodies in mice upon vaccination

BACKGROUND: Urease B is an important virulence factor that is required for Helicobacter pylori to colonise the gastric mucosa. Mouse monoclonal antibodies (mAbs) that inhibit urease B enzymatic activity will be useful as vaccines for the prevention and treatment of H. pylori infection. Here, we prod...

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Detalles Bibliográficos
Autores principales: Li, Yan, Ning, Yunshan, Wang, Yundan, Peng, Dandan, Jiang, Yaodong, Zhang, Lili, Long, Min, Luo, Jun, Li, Ming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012656/
https://www.ncbi.nlm.nih.gov/pubmed/21118490
http://dx.doi.org/10.1186/1472-6750-10-84

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