High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients

BACKGROUND: Peutz-Jeghers syndrome (PJS) is a rare autosomal dominantly inherited disease characterized by gastrointestinal hamartomatous polyposis and mucocutaneous pigmentation. The genetic predisposition for PJS has been shown to be associated with germline mutations in the STK11/LKB1 tumor suppr...

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Detalles Bibliográficos
Autores principales: Papp, Janos, Kovacs, Marietta Eva, Solyom, Szilvia, Kasler, Miklos, Børresen-Dale, Anne-Lise, Olah, Edith
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012662/
https://www.ncbi.nlm.nih.gov/pubmed/21118512
http://dx.doi.org/10.1186/1471-2350-11-169

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