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Age and sex dependent changes in liver gene expression during the life cycle of the rat
BACKGROUND: Age- and sex-related susceptibility to adverse drug reactions and disease is a key concern in understanding drug safety and disease progression. We hypothesize that the underlying suite of hepatic genes expressed at various life cycle stages will impact susceptibility to adverse drug rea...
Autores principales: | Kwekel, Joshua C, Desai , Varsha G, Moland, Carrie L, Branham, William S, Fuscoe, James C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012673/ https://www.ncbi.nlm.nih.gov/pubmed/21118493 http://dx.doi.org/10.1186/1471-2164-11-675 |
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