Cargando…
The NOD2 Single Nucleotide Polymorphisms rs2066843 and rs2076756 Are Novel and Common Crohn's Disease Susceptibility Gene Variants
BACKGROUND: The aims were to analyze two novel NOD2 variants (rs2066843 and rs2076756) in a large cohort of patients with inflammatory bowel disease and to elucidate phenotypic consequences. METHODOLOGY/PRINCIPAL FINDINGS: Genomic DNA from 2700 Caucasians including 812 patients with Crohn's dis...
Autores principales: | Glas, Jürgen, Seiderer, Julia, Tillack, Cornelia, Pfennig, Simone, Beigel, Florian, Jürgens, Matthias, Olszak, Torsten, Laubender, Rüdiger P., Weidinger, Maria, Müller-Myhsok, Bertram, Göke, Burkhard, Ochsenkühn, Thomas, Lohse, Peter, Diegelmann, Julia, Czamara, Darina, Brand, Stephan |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012690/ https://www.ncbi.nlm.nih.gov/pubmed/21209938 http://dx.doi.org/10.1371/journal.pone.0014466 |
Ejemplares similares
-
CEACAM6 Gene Variants in Inflammatory Bowel Disease
por: Glas, Jürgen, et al.
Publicado: (2011) -
Evidence for STAT4 as a Common Autoimmune Gene: rs7574865 Is Associated with Colonic Crohn's Disease and Early Disease Onset
por: Glas, Jürgen, et al.
Publicado: (2010) -
The NOD2 p.Leu1007fsX1008 Mutation (rs2066847) Is a Stronger Predictor of the Clinical Course of Crohn's Disease than the FOXO3A Intron Variant rs12212067
por: Schnitzler, Fabian, et al.
Publicado: (2014) -
The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations
por: Schnitzler, Fabian, et al.
Publicado: (2015) -
PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Colitis Supporting a Common Genetic Disease Background
por: Glas, Jürgen, et al.
Publicado: (2012)