Molecular Determinants of Survival Motor Neuron (SMN) Protein Cleavage by the Calcium-Activated Protease, Calpain

Spinal muscular atrophy (SMA) is a leading genetic cause of childhood mortality, caused by reduced levels of survival motor neuron (SMN) protein. SMN functions as part of a large complex in the biogenesis of small nuclear ribonucleoproteins (snRNPs). It is not clear if defects in snRNP biogenesis ca...

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Detalles Bibliográficos
Autores principales: Fuentes, Jennifer L., Strayer, Molly S., Matera, A. Gregory
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012718/
https://www.ncbi.nlm.nih.gov/pubmed/21209906
http://dx.doi.org/10.1371/journal.pone.0015769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012718/
https://www.ncbi.nlm.nih.gov/pubmed/21209906
http://dx.doi.org/10.1371/journal.pone.0015769

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