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The HIV-1 Integrase α4-Helix Involved in LTR-DNA Recognition Is also a Highly Antigenic Peptide Element

Monoclonal antibodies (MAbas) constitute remarkable tools to analyze the relationship between the structure and the function of a protein. By immunizing a mouse with a 29mer peptide (K159) formed by residues 147 to 175 of the HIV-1 integrase (IN), we obtained a monoclonal antibody (MAba4) recognizin...

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Detalles Bibliográficos
Autores principales:	Azzi, Sandy, Parissi, Vincent, Maroun, Richard G., Eid, Pierre, Mauffret, Olivier, Fermandjian, Serge
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012736/ https://www.ncbi.nlm.nih.gov/pubmed/21209864 http://dx.doi.org/10.1371/journal.pone.0016001

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