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Fatal Cases of 2009 Pandemic Influenza A (H1N1) in Korea
The aim of this study was to describe the features of deaths associated with the 2009 pandemic influenza A (H1N1) by 26 November 2009 in Korea. We collected standardized case reports on 115 confirmed deaths through a nationwide enhanced influenza surveillance system. The median age was 61 yr (interq...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Korean Academy of Medical Sciences
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012845/ https://www.ncbi.nlm.nih.gov/pubmed/21218025 http://dx.doi.org/10.3346/jkms.2011.26.1.22 |
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author | Kim, Hyun Su Kim, Joon Hyung Shin, Soo Youn Kang, Young A Lee, Ha Gyung Kim, Jin Seok Lee, Jong Koo Cho, Belong |
author_facet | Kim, Hyun Su Kim, Joon Hyung Shin, Soo Youn Kang, Young A Lee, Ha Gyung Kim, Jin Seok Lee, Jong Koo Cho, Belong |
author_sort | Kim, Hyun Su |
collection | PubMed |
description | The aim of this study was to describe the features of deaths associated with the 2009 pandemic influenza A (H1N1) by 26 November 2009 in Korea. We collected standardized case reports on 115 confirmed deaths through a nationwide enhanced influenza surveillance system. The median age was 61 yr (interquartile range [IQR], 0.2-97 yr) and 58 (50.4%) were females. The case fatality rate was estimated as 16 per 100,000 cases. The age-related mortality rate had a J-shaped curve. Eighty-three patients (72.2%) had at least 1 underlying medical disease. Bacterial co-infections were detected in the blood or sputum specimens from 34 patients. Of the 63 patients who were hospitalized in the intensive care unit (ICU), the median time from symptom onset to hospital admission was 2 days (IQR, 0-22 days), and the median time from hospitalization to ICU admission was 1 day (IQR, 0-17 days). Neuraminidase inhibitors were administered to 100 patients (87.0%), 36% of whom began treatment within 2 days. In conclusion, fatal cases from the 2009 influenza A (H1N1) infection in Korea are mainly aged individuals with underlying disease, and associated with pneumonia, bacterial co-infections, and multi-organ failure. |
format | Text |
id | pubmed-3012845 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-30128452011-01-08 Fatal Cases of 2009 Pandemic Influenza A (H1N1) in Korea Kim, Hyun Su Kim, Joon Hyung Shin, Soo Youn Kang, Young A Lee, Ha Gyung Kim, Jin Seok Lee, Jong Koo Cho, Belong J Korean Med Sci Original Article The aim of this study was to describe the features of deaths associated with the 2009 pandemic influenza A (H1N1) by 26 November 2009 in Korea. We collected standardized case reports on 115 confirmed deaths through a nationwide enhanced influenza surveillance system. The median age was 61 yr (interquartile range [IQR], 0.2-97 yr) and 58 (50.4%) were females. The case fatality rate was estimated as 16 per 100,000 cases. The age-related mortality rate had a J-shaped curve. Eighty-three patients (72.2%) had at least 1 underlying medical disease. Bacterial co-infections were detected in the blood or sputum specimens from 34 patients. Of the 63 patients who were hospitalized in the intensive care unit (ICU), the median time from symptom onset to hospital admission was 2 days (IQR, 0-22 days), and the median time from hospitalization to ICU admission was 1 day (IQR, 0-17 days). Neuraminidase inhibitors were administered to 100 patients (87.0%), 36% of whom began treatment within 2 days. In conclusion, fatal cases from the 2009 influenza A (H1N1) infection in Korea are mainly aged individuals with underlying disease, and associated with pneumonia, bacterial co-infections, and multi-organ failure. The Korean Academy of Medical Sciences 2011-01 2010-12-22 /pmc/articles/PMC3012845/ /pubmed/21218025 http://dx.doi.org/10.3346/jkms.2011.26.1.22 Text en © 2011 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Hyun Su Kim, Joon Hyung Shin, Soo Youn Kang, Young A Lee, Ha Gyung Kim, Jin Seok Lee, Jong Koo Cho, Belong Fatal Cases of 2009 Pandemic Influenza A (H1N1) in Korea |
title | Fatal Cases of 2009 Pandemic Influenza A (H1N1) in Korea |
title_full | Fatal Cases of 2009 Pandemic Influenza A (H1N1) in Korea |
title_fullStr | Fatal Cases of 2009 Pandemic Influenza A (H1N1) in Korea |
title_full_unstemmed | Fatal Cases of 2009 Pandemic Influenza A (H1N1) in Korea |
title_short | Fatal Cases of 2009 Pandemic Influenza A (H1N1) in Korea |
title_sort | fatal cases of 2009 pandemic influenza a (h1n1) in korea |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012845/ https://www.ncbi.nlm.nih.gov/pubmed/21218025 http://dx.doi.org/10.3346/jkms.2011.26.1.22 |
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