A COMPARISON OF A DIVIDED AND A SINGLE DOSE REGIME OF DOTHIEPIN AND ITS THERAPEUTIC EFFICACY

In a double-blind study the advantages of a once-a-day dosage of a tricyclic antidepressant as against a thrice daily dosage regimen was evaluated using dothiepin (Prothiaden) and matching placebo tablets. Twenty eight adult patients of both sexes participated in the study and were randomly allocate...

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Detalles Bibliográficos
Autor principal: Sharma, S. D.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1981
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012909/
https://www.ncbi.nlm.nih.gov/pubmed/22058563
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author Sharma, S. D.
author_facet Sharma, S. D.
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description In a double-blind study the advantages of a once-a-day dosage of a tricyclic antidepressant as against a thrice daily dosage regimen was evaluated using dothiepin (Prothiaden) and matching placebo tablets. Twenty eight adult patients of both sexes participated in the study and were randomly allocated to drug treatment. Out of 28 patients who received dothiepin, 17 showed good improvement, in 6 improvement was fair and in 5 there was no improvement. These findings show that the response to dotheipin was satisfactory. Further, both treatments were equally effective in relieving symptoms of depression.
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spelling pubmed-30129092011-11-06 A COMPARISON OF A DIVIDED AND A SINGLE DOSE REGIME OF DOTHIEPIN AND ITS THERAPEUTIC EFFICACY Sharma, S. D. Indian J Psychiatry Original Article In a double-blind study the advantages of a once-a-day dosage of a tricyclic antidepressant as against a thrice daily dosage regimen was evaluated using dothiepin (Prothiaden) and matching placebo tablets. Twenty eight adult patients of both sexes participated in the study and were randomly allocated to drug treatment. Out of 28 patients who received dothiepin, 17 showed good improvement, in 6 improvement was fair and in 5 there was no improvement. These findings show that the response to dotheipin was satisfactory. Further, both treatments were equally effective in relieving symptoms of depression. Medknow Publications 1981 /pmc/articles/PMC3012909/ /pubmed/22058563 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Sharma, S. D.
A COMPARISON OF A DIVIDED AND A SINGLE DOSE REGIME OF DOTHIEPIN AND ITS THERAPEUTIC EFFICACY
title A COMPARISON OF A DIVIDED AND A SINGLE DOSE REGIME OF DOTHIEPIN AND ITS THERAPEUTIC EFFICACY
title_full A COMPARISON OF A DIVIDED AND A SINGLE DOSE REGIME OF DOTHIEPIN AND ITS THERAPEUTIC EFFICACY
title_fullStr A COMPARISON OF A DIVIDED AND A SINGLE DOSE REGIME OF DOTHIEPIN AND ITS THERAPEUTIC EFFICACY
title_full_unstemmed A COMPARISON OF A DIVIDED AND A SINGLE DOSE REGIME OF DOTHIEPIN AND ITS THERAPEUTIC EFFICACY
title_short A COMPARISON OF A DIVIDED AND A SINGLE DOSE REGIME OF DOTHIEPIN AND ITS THERAPEUTIC EFFICACY
title_sort comparison of a divided and a single dose regime of dothiepin and its therapeutic efficacy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012909/
https://www.ncbi.nlm.nih.gov/pubmed/22058563
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