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Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progressioan

BACKGROUND: Aldo-keto reductase (AKR) 1C family member 3 (AKR1C3), one of four identified human AKR1C enzymes, catalyzes steroid, prostaglandin, and xenobiotic metabolism. In the prostate, AKR1C3 is up-regulated in localized and advanced prostate adenocarcinoma, and is associated with prostate cance...

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Detalles Bibliográficos
Autores principales:	Dozmorov, Mikhail G, Azzarello, Joseph T, Wren, Jonathan D, Fung, Kar-Ming, Yang, Qing, Davis, Jeffrey S, Hurst, Robert E, Culkin, Daniel J, Penning, Trevor M, Lin, Hsueh-Kung
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013086/ https://www.ncbi.nlm.nih.gov/pubmed/21134280 http://dx.doi.org/10.1186/1471-2407-10-672

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