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Turnover of BRCA1 Involves in Radiation-Induced Apoptosis
BACKGROUND: Germ-line mutations of the breast cancer susceptibility gene-1 (BRCA1) increase the susceptibility to tumorigenesis. The function of BRCA1 is to regulate critical cellular processes, including cell cycle progression, genomic integrity, and apoptosis. Studies on the regulation of BRCA1 ha...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013096/ https://www.ncbi.nlm.nih.gov/pubmed/21217819 http://dx.doi.org/10.1371/journal.pone.0014484 |