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Turnover of BRCA1 Involves in Radiation-Induced Apoptosis

BACKGROUND: Germ-line mutations of the breast cancer susceptibility gene-1 (BRCA1) increase the susceptibility to tumorigenesis. The function of BRCA1 is to regulate critical cellular processes, including cell cycle progression, genomic integrity, and apoptosis. Studies on the regulation of BRCA1 ha...

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Detalles Bibliográficos
Autores principales:	Liu, Weijun, Zong, Wenjun, Wu, George, Fujita, Takeo, Li, Wenqi, Wu, Judy, Wan, Yong
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013096/ https://www.ncbi.nlm.nih.gov/pubmed/21217819 http://dx.doi.org/10.1371/journal.pone.0014484

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