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RNAi Screen of DAF-16/FOXO Target Genes in C. elegans Links Pathogenesis and Dauer Formation

The DAF-16/FOXO transcription factor is the major downstream output of the insulin/IGF1R signaling pathway controlling C. elegans dauer larva development and aging. To identify novel downstream genes affecting dauer formation, we used RNAi to screen candidate genes previously identified to be regula...

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Detalles Bibliográficos
Autores principales:	Jensen, Victor L., Simonsen, Karina T., Lee, Yu-Hui, Park, Donha, Riddle, Donald L.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013133/ https://www.ncbi.nlm.nih.gov/pubmed/21209831 http://dx.doi.org/10.1371/journal.pone.0015902

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