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The Molecular Chaperone Hsp90α Is Required for Meiotic Progression of Spermatocytes beyond Pachytene in the Mouse

The molecular chaperone Hsp90 has been found to be essential for viability in all tested eukaryotes, from the budding yeast to Drosophila. In mammals, two genes encode the two highly similar and functionally largely redundant isoforms Hsp90α and Hsp90β. Although they are co-expressed in most if not...

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Detalles Bibliográficos
Autores principales: Grad, Iwona, Cederroth, Christopher R., Walicki, Joël, Grey, Corinne, Barluenga, Sofia, Winssinger, Nicolas, De Massy, Bernard, Nef, Serge, Picard, Didier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013136/
https://www.ncbi.nlm.nih.gov/pubmed/21209834
http://dx.doi.org/10.1371/journal.pone.0015770