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Characterization of New Otic Enhancers of the Pou3f4 Gene Reveal Distinct Signaling Pathway Regulation and Spatio-Temporal Patterns

POU3F4 is a member of the POU-homedomain transcription factor family with a prominent role in inner ear development. Mutations in the human POU3F4 coding unit leads to X-linked deafness type 3 (DFN3), characterized by conductive hearing loss and progressive sensorineural deafness. Microdeletions fou...

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Detalles Bibliográficos
Autores principales:	Robert-Moreno, Àlex, Naranjo, Silvia, de la Calle-Mustienes, Elisa, Gómez-Skarmeta, José Luis, Alsina, Berta
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013142/ https://www.ncbi.nlm.nih.gov/pubmed/21209840 http://dx.doi.org/10.1371/journal.pone.0015907

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