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A New Peptide Ligand for Targeting Human Carbonic Anhydrase IX, Identified through the Phage Display Technology
Carbonic anhydrase IX (CAIX) is a transmembrane enzyme found to be overexpressed in various tumors and associated with tumor hypoxia. Ligands binding this target may be used to visualize hypoxia, tumor manifestation or treat tumors by endoradiotherapy. METHODS: Phage display was performed with a 12...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013143/ https://www.ncbi.nlm.nih.gov/pubmed/21209841 http://dx.doi.org/10.1371/journal.pone.0015962 |