A New Peptide Ligand for Targeting Human Carbonic Anhydrase IX, Identified through the Phage Display Technology

Carbonic anhydrase IX (CAIX) is a transmembrane enzyme found to be overexpressed in various tumors and associated with tumor hypoxia. Ligands binding this target may be used to visualize hypoxia, tumor manifestation or treat tumors by endoradiotherapy. METHODS: Phage display was performed with a 12...

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Detalles Bibliográficos
Autores principales: Askoxylakis, Vasileios, Garcia-Boy, Regine, Rana, Shoaib, Krämer, Susanne, Hebling, Ulrike, Mier, Walter, Altmann, Annette, Markert, Annette, Debus, Jürgen, Haberkorn, Uwe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013143/
https://www.ncbi.nlm.nih.gov/pubmed/21209841
http://dx.doi.org/10.1371/journal.pone.0015962

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