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Effective—a database of predicted secreted bacterial proteins
Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins (‘effectors’) crucial for understanding the molecular bacterium–host interactions. Effective (http://effectors.org) is a database of predicted bacterial secreted pr...
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013723/ https://www.ncbi.nlm.nih.gov/pubmed/21071416 http://dx.doi.org/10.1093/nar/gkq1154 |
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author | Jehl, Marc-André Arnold, Roland Rattei, Thomas |
author_facet | Jehl, Marc-André Arnold, Roland Rattei, Thomas |
author_sort | Jehl, Marc-André |
collection | PubMed |
description | Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins (‘effectors’) crucial for understanding the molecular bacterium–host interactions. Effective (http://effectors.org) is a database of predicted bacterial secreted proteins, implementing two complementary prediction strategies for protein secretion: the identification of eukaryotic-like protein domains and the recognition of signal peptides in amino acid sequences. The Effective web portal provides user-friendly tools for browsing and retrieving comprehensive precalculated predictions for whole bacterial genomes as well as for the interactive prediction of effectors in user-provided protein sequences. |
format | Text |
id | pubmed-3013723 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-30137232011-01-03 Effective—a database of predicted secreted bacterial proteins Jehl, Marc-André Arnold, Roland Rattei, Thomas Nucleic Acids Res Articles Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins (‘effectors’) crucial for understanding the molecular bacterium–host interactions. Effective (http://effectors.org) is a database of predicted bacterial secreted proteins, implementing two complementary prediction strategies for protein secretion: the identification of eukaryotic-like protein domains and the recognition of signal peptides in amino acid sequences. The Effective web portal provides user-friendly tools for browsing and retrieving comprehensive precalculated predictions for whole bacterial genomes as well as for the interactive prediction of effectors in user-provided protein sequences. Oxford University Press 2011-01 2010-11-11 /pmc/articles/PMC3013723/ /pubmed/21071416 http://dx.doi.org/10.1093/nar/gkq1154 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Jehl, Marc-André Arnold, Roland Rattei, Thomas Effective—a database of predicted secreted bacterial proteins |
title | Effective—a database of predicted secreted bacterial proteins |
title_full | Effective—a database of predicted secreted bacterial proteins |
title_fullStr | Effective—a database of predicted secreted bacterial proteins |
title_full_unstemmed | Effective—a database of predicted secreted bacterial proteins |
title_short | Effective—a database of predicted secreted bacterial proteins |
title_sort | effective—a database of predicted secreted bacterial proteins |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013723/ https://www.ncbi.nlm.nih.gov/pubmed/21071416 http://dx.doi.org/10.1093/nar/gkq1154 |
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