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ConsensusPathDB: toward a more complete picture of cell biology
ConsensusPathDB is a meta-database that integrates different types of functional interactions from heterogeneous interaction data resources. Physical protein interactions, metabolic and signaling reactions and gene regulatory interactions are integrated in a seamless functional association network t...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013724/ https://www.ncbi.nlm.nih.gov/pubmed/21071422 http://dx.doi.org/10.1093/nar/gkq1156 |
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author | Kamburov, Atanas Pentchev, Konstantin Galicka, Hanna Wierling, Christoph Lehrach, Hans Herwig, Ralf |
author_facet | Kamburov, Atanas Pentchev, Konstantin Galicka, Hanna Wierling, Christoph Lehrach, Hans Herwig, Ralf |
author_sort | Kamburov, Atanas |
collection | PubMed |
description | ConsensusPathDB is a meta-database that integrates different types of functional interactions from heterogeneous interaction data resources. Physical protein interactions, metabolic and signaling reactions and gene regulatory interactions are integrated in a seamless functional association network that simultaneously describes multiple functional aspects of genes, proteins, complexes, metabolites, etc. With 155 432 human, 194 480 yeast and 13 648 mouse complex functional interactions (originating from 18 databases on human and eight databases on yeast and mouse interactions each), ConsensusPathDB currently constitutes the most comprehensive publicly available interaction repository for these species. The Web interface at http://cpdb.molgen.mpg.de offers different ways of utilizing these integrated interaction data, in particular with tools for visualization, analysis and interpretation of high-throughput expression data in the light of functional interactions and biological pathways. |
format | Text |
id | pubmed-3013724 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-30137242011-01-03 ConsensusPathDB: toward a more complete picture of cell biology Kamburov, Atanas Pentchev, Konstantin Galicka, Hanna Wierling, Christoph Lehrach, Hans Herwig, Ralf Nucleic Acids Res Articles ConsensusPathDB is a meta-database that integrates different types of functional interactions from heterogeneous interaction data resources. Physical protein interactions, metabolic and signaling reactions and gene regulatory interactions are integrated in a seamless functional association network that simultaneously describes multiple functional aspects of genes, proteins, complexes, metabolites, etc. With 155 432 human, 194 480 yeast and 13 648 mouse complex functional interactions (originating from 18 databases on human and eight databases on yeast and mouse interactions each), ConsensusPathDB currently constitutes the most comprehensive publicly available interaction repository for these species. The Web interface at http://cpdb.molgen.mpg.de offers different ways of utilizing these integrated interaction data, in particular with tools for visualization, analysis and interpretation of high-throughput expression data in the light of functional interactions and biological pathways. Oxford University Press 2011-01 2010-11-11 /pmc/articles/PMC3013724/ /pubmed/21071422 http://dx.doi.org/10.1093/nar/gkq1156 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Kamburov, Atanas Pentchev, Konstantin Galicka, Hanna Wierling, Christoph Lehrach, Hans Herwig, Ralf ConsensusPathDB: toward a more complete picture of cell biology |
title | ConsensusPathDB: toward a more complete picture of cell biology |
title_full | ConsensusPathDB: toward a more complete picture of cell biology |
title_fullStr | ConsensusPathDB: toward a more complete picture of cell biology |
title_full_unstemmed | ConsensusPathDB: toward a more complete picture of cell biology |
title_short | ConsensusPathDB: toward a more complete picture of cell biology |
title_sort | consensuspathdb: toward a more complete picture of cell biology |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013724/ https://www.ncbi.nlm.nih.gov/pubmed/21071422 http://dx.doi.org/10.1093/nar/gkq1156 |
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