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MIPS: curated databases and comprehensive secondary data resources in 2010
The Munich Information Center for Protein Sequences (MIPS at the Helmholtz Center for Environmental Health, Neuherberg, Germany) has many years of experience in providing annotated collections of biological data. Selected data sets of high relevance, such as model genomes, are subjected to careful m...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013725/ https://www.ncbi.nlm.nih.gov/pubmed/21109531 http://dx.doi.org/10.1093/nar/gkq1157 |
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author | Mewes, H. Werner Ruepp, Andreas Theis, Fabian Rattei, Thomas Walter, Mathias Frishman, Dmitrij Suhre, Karsten Spannagl, Manuel Mayer, Klaus F.X. Stümpflen, Volker Antonov, Alexey |
author_facet | Mewes, H. Werner Ruepp, Andreas Theis, Fabian Rattei, Thomas Walter, Mathias Frishman, Dmitrij Suhre, Karsten Spannagl, Manuel Mayer, Klaus F.X. Stümpflen, Volker Antonov, Alexey |
author_sort | Mewes, H. Werner |
collection | PubMed |
description | The Munich Information Center for Protein Sequences (MIPS at the Helmholtz Center for Environmental Health, Neuherberg, Germany) has many years of experience in providing annotated collections of biological data. Selected data sets of high relevance, such as model genomes, are subjected to careful manual curation, while the bulk of high-throughput data is annotated by automatic means. High-quality reference resources developed in the past and still actively maintained include Saccharomyces cerevisiae, Neurospora crassa and Arabidopsis thaliana genome databases as well as several protein interaction data sets (MPACT, MPPI and CORUM). More recent projects are PhenomiR, the database on microRNA-related phenotypes, and MIPS PlantsDB for integrative and comparative plant genome research. The interlinked resources SIMAP and PEDANT provide homology relationships as well as up-to-date and consistent annotation for 38 000 000 protein sequences. PPLIPS and CCancer are versatile tools for proteomics and functional genomics interfacing to a database of compilations from gene lists extracted from literature. A novel literature-mining tool, EXCERBT, gives access to structured information on classified relations between genes, proteins, phenotypes and diseases extracted from Medline abstracts by semantic analysis. All databases described here, as well as the detailed descriptions of our projects can be accessed through the MIPS WWW server (http://mips.helmholtz-muenchen.de). |
format | Text |
id | pubmed-3013725 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-30137252011-01-03 MIPS: curated databases and comprehensive secondary data resources in 2010 Mewes, H. Werner Ruepp, Andreas Theis, Fabian Rattei, Thomas Walter, Mathias Frishman, Dmitrij Suhre, Karsten Spannagl, Manuel Mayer, Klaus F.X. Stümpflen, Volker Antonov, Alexey Nucleic Acids Res Articles The Munich Information Center for Protein Sequences (MIPS at the Helmholtz Center for Environmental Health, Neuherberg, Germany) has many years of experience in providing annotated collections of biological data. Selected data sets of high relevance, such as model genomes, are subjected to careful manual curation, while the bulk of high-throughput data is annotated by automatic means. High-quality reference resources developed in the past and still actively maintained include Saccharomyces cerevisiae, Neurospora crassa and Arabidopsis thaliana genome databases as well as several protein interaction data sets (MPACT, MPPI and CORUM). More recent projects are PhenomiR, the database on microRNA-related phenotypes, and MIPS PlantsDB for integrative and comparative plant genome research. The interlinked resources SIMAP and PEDANT provide homology relationships as well as up-to-date and consistent annotation for 38 000 000 protein sequences. PPLIPS and CCancer are versatile tools for proteomics and functional genomics interfacing to a database of compilations from gene lists extracted from literature. A novel literature-mining tool, EXCERBT, gives access to structured information on classified relations between genes, proteins, phenotypes and diseases extracted from Medline abstracts by semantic analysis. All databases described here, as well as the detailed descriptions of our projects can be accessed through the MIPS WWW server (http://mips.helmholtz-muenchen.de). Oxford University Press 2011-01 2010-11-24 /pmc/articles/PMC3013725/ /pubmed/21109531 http://dx.doi.org/10.1093/nar/gkq1157 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Mewes, H. Werner Ruepp, Andreas Theis, Fabian Rattei, Thomas Walter, Mathias Frishman, Dmitrij Suhre, Karsten Spannagl, Manuel Mayer, Klaus F.X. Stümpflen, Volker Antonov, Alexey MIPS: curated databases and comprehensive secondary data resources in 2010 |
title | MIPS: curated databases and comprehensive secondary data resources in 2010 |
title_full | MIPS: curated databases and comprehensive secondary data resources in 2010 |
title_fullStr | MIPS: curated databases and comprehensive secondary data resources in 2010 |
title_full_unstemmed | MIPS: curated databases and comprehensive secondary data resources in 2010 |
title_short | MIPS: curated databases and comprehensive secondary data resources in 2010 |
title_sort | mips: curated databases and comprehensive secondary data resources in 2010 |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013725/ https://www.ncbi.nlm.nih.gov/pubmed/21109531 http://dx.doi.org/10.1093/nar/gkq1157 |
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