BSDB: the biomolecule stretching database

We describe the Biomolecule Stretching Data Base that has been recently set up at http://www.ifpan.edu.pl/BSDB/. It provides information about mechanostability of proteins. Its core is based on simulations of stretching of 17 134 proteins within a structure-based model. The primary information is ab...

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Detalles Bibliográficos
Autores principales: Sikora, Mateusz, Sułkowska, Joanna I., Witkowski, Bartłomiej S., Cieplak, Marek
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013760/
https://www.ncbi.nlm.nih.gov/pubmed/20929872
http://dx.doi.org/10.1093/nar/gkq851
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author Sikora, Mateusz
Sułkowska, Joanna I.
Witkowski, Bartłomiej S.
Cieplak, Marek
author_facet Sikora, Mateusz
Sułkowska, Joanna I.
Witkowski, Bartłomiej S.
Cieplak, Marek
author_sort Sikora, Mateusz
collection PubMed
description We describe the Biomolecule Stretching Data Base that has been recently set up at http://www.ifpan.edu.pl/BSDB/. It provides information about mechanostability of proteins. Its core is based on simulations of stretching of 17 134 proteins within a structure-based model. The primary information is about the heights of the maximal force peaks, the force–displacement patterns, and the sequencing of the contact-rupturing events. We also summarize the possible types of the mechanical clamps, i.e. the motifs which are responsible for a protein's resistance to stretching.
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spelling pubmed-30137602011-01-03 BSDB: the biomolecule stretching database Sikora, Mateusz Sułkowska, Joanna I. Witkowski, Bartłomiej S. Cieplak, Marek Nucleic Acids Res Articles We describe the Biomolecule Stretching Data Base that has been recently set up at http://www.ifpan.edu.pl/BSDB/. It provides information about mechanostability of proteins. Its core is based on simulations of stretching of 17 134 proteins within a structure-based model. The primary information is about the heights of the maximal force peaks, the force–displacement patterns, and the sequencing of the contact-rupturing events. We also summarize the possible types of the mechanical clamps, i.e. the motifs which are responsible for a protein's resistance to stretching. Oxford University Press 2011-01 2010-10-06 /pmc/articles/PMC3013760/ /pubmed/20929872 http://dx.doi.org/10.1093/nar/gkq851 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Sikora, Mateusz
Sułkowska, Joanna I.
Witkowski, Bartłomiej S.
Cieplak, Marek
BSDB: the biomolecule stretching database
title BSDB: the biomolecule stretching database
title_full BSDB: the biomolecule stretching database
title_fullStr BSDB: the biomolecule stretching database
title_full_unstemmed BSDB: the biomolecule stretching database
title_short BSDB: the biomolecule stretching database
title_sort bsdb: the biomolecule stretching database
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013760/
https://www.ncbi.nlm.nih.gov/pubmed/20929872
http://dx.doi.org/10.1093/nar/gkq851
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AT sułkowskajoannai bsdbthebiomoleculestretchingdatabase
AT witkowskibartłomiejs bsdbthebiomoleculestretchingdatabase
AT cieplakmarek bsdbthebiomoleculestretchingdatabase

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