FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system

FlyFactorSurvey (http://pgfe.umassmed.edu/TFDBS/) is a database of DNA binding specificities for Drosophila transcription factors (TFs) primarily determined using the bacterial one-hybrid system. The database provides community access to over 400 recognition motifs and position weight matrices for o...

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Autores principales: Zhu, Lihua Julie, Christensen, Ryan G., Kazemian, Majid, Hull, Christopher J., Enuameh, Metewo Selase, Basciotta, Matthew D., Brasefield, Jessie A., Zhu, Cong, Asriyan, Yuna, Lapointe, David S., Sinha, Saurabh, Wolfe, Scot A., Brodsky, Michael H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013762/
https://www.ncbi.nlm.nih.gov/pubmed/21097781
http://dx.doi.org/10.1093/nar/gkq858
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author Zhu, Lihua Julie
Christensen, Ryan G.
Kazemian, Majid
Hull, Christopher J.
Enuameh, Metewo Selase
Basciotta, Matthew D.
Brasefield, Jessie A.
Zhu, Cong
Asriyan, Yuna
Lapointe, David S.
Sinha, Saurabh
Wolfe, Scot A.
Brodsky, Michael H.
author_facet Zhu, Lihua Julie
Christensen, Ryan G.
Kazemian, Majid
Hull, Christopher J.
Enuameh, Metewo Selase
Basciotta, Matthew D.
Brasefield, Jessie A.
Zhu, Cong
Asriyan, Yuna
Lapointe, David S.
Sinha, Saurabh
Wolfe, Scot A.
Brodsky, Michael H.
author_sort Zhu, Lihua Julie
collection PubMed
description FlyFactorSurvey (http://pgfe.umassmed.edu/TFDBS/) is a database of DNA binding specificities for Drosophila transcription factors (TFs) primarily determined using the bacterial one-hybrid system. The database provides community access to over 400 recognition motifs and position weight matrices for over 200 TFs, including many unpublished motifs. Search tools and flat file downloads are provided to retrieve binding site information (as sequences, matrices and sequence logos) for individual TFs, groups of TFs or for all TFs with characterized binding specificities. Linked analysis tools allow users to identify motifs within our database that share similarity to a query matrix or to view the distribution of occurrences of an individual motif throughout the Drosophila genome. Together, this database and its associated tools provide computational and experimental biologists with resources to predict interactions between Drosophila TFs and target cis-regulatory sequences.
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spelling pubmed-30137622011-01-03 FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system Zhu, Lihua Julie Christensen, Ryan G. Kazemian, Majid Hull, Christopher J. Enuameh, Metewo Selase Basciotta, Matthew D. Brasefield, Jessie A. Zhu, Cong Asriyan, Yuna Lapointe, David S. Sinha, Saurabh Wolfe, Scot A. Brodsky, Michael H. Nucleic Acids Res Articles FlyFactorSurvey (http://pgfe.umassmed.edu/TFDBS/) is a database of DNA binding specificities for Drosophila transcription factors (TFs) primarily determined using the bacterial one-hybrid system. The database provides community access to over 400 recognition motifs and position weight matrices for over 200 TFs, including many unpublished motifs. Search tools and flat file downloads are provided to retrieve binding site information (as sequences, matrices and sequence logos) for individual TFs, groups of TFs or for all TFs with characterized binding specificities. Linked analysis tools allow users to identify motifs within our database that share similarity to a query matrix or to view the distribution of occurrences of an individual motif throughout the Drosophila genome. Together, this database and its associated tools provide computational and experimental biologists with resources to predict interactions between Drosophila TFs and target cis-regulatory sequences. Oxford University Press 2011-01 2010-11-19 /pmc/articles/PMC3013762/ /pubmed/21097781 http://dx.doi.org/10.1093/nar/gkq858 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Zhu, Lihua Julie
Christensen, Ryan G.
Kazemian, Majid
Hull, Christopher J.
Enuameh, Metewo Selase
Basciotta, Matthew D.
Brasefield, Jessie A.
Zhu, Cong
Asriyan, Yuna
Lapointe, David S.
Sinha, Saurabh
Wolfe, Scot A.
Brodsky, Michael H.
FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system
title FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system
title_full FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system
title_fullStr FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system
title_full_unstemmed FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system
title_short FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system
title_sort flyfactorsurvey: a database of drosophila transcription factor binding specificities determined using the bacterial one-hybrid system
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013762/
https://www.ncbi.nlm.nih.gov/pubmed/21097781
http://dx.doi.org/10.1093/nar/gkq858
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