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T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
T1DBase (http://www.t1dbase.org) is web platform, which supports the type 1 diabetes (T1D) community. It integrates genetic, genomic and expression data relevant to T1D research across mouse, rat and human and presents this to the user as a set of web pages and tools. This update describes the incor...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013780/ https://www.ncbi.nlm.nih.gov/pubmed/20937630 http://dx.doi.org/10.1093/nar/gkq912 |
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author | Burren, Oliver S. Adlem, Ellen C. Achuthan, Premanand Christensen, Mikkel Coulson, Richard M. R. Todd, John A. |
author_facet | Burren, Oliver S. Adlem, Ellen C. Achuthan, Premanand Christensen, Mikkel Coulson, Richard M. R. Todd, John A. |
author_sort | Burren, Oliver S. |
collection | PubMed |
description | T1DBase (http://www.t1dbase.org) is web platform, which supports the type 1 diabetes (T1D) community. It integrates genetic, genomic and expression data relevant to T1D research across mouse, rat and human and presents this to the user as a set of web pages and tools. This update describes the incorporation of new data sets, tools and curation efforts as well as a new website design to simplify site use. New data sets include curated summary data from four genome-wide association studies relevant to T1D, HaemAtlas—a data set and tool to query gene expression levels in haematopoietic cells and a manually curated table of human T1D susceptibility loci, incorporating genetic overlap with other related diseases. These developments will continue to support T1D research and allow easy access to large and complex T1D relevant data sets. |
format | Text |
id | pubmed-3013780 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-30137802011-01-03 T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research Burren, Oliver S. Adlem, Ellen C. Achuthan, Premanand Christensen, Mikkel Coulson, Richard M. R. Todd, John A. Nucleic Acids Res Articles T1DBase (http://www.t1dbase.org) is web platform, which supports the type 1 diabetes (T1D) community. It integrates genetic, genomic and expression data relevant to T1D research across mouse, rat and human and presents this to the user as a set of web pages and tools. This update describes the incorporation of new data sets, tools and curation efforts as well as a new website design to simplify site use. New data sets include curated summary data from four genome-wide association studies relevant to T1D, HaemAtlas—a data set and tool to query gene expression levels in haematopoietic cells and a manually curated table of human T1D susceptibility loci, incorporating genetic overlap with other related diseases. These developments will continue to support T1D research and allow easy access to large and complex T1D relevant data sets. Oxford University Press 2011-01 2010-10-11 /pmc/articles/PMC3013780/ /pubmed/20937630 http://dx.doi.org/10.1093/nar/gkq912 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Burren, Oliver S. Adlem, Ellen C. Achuthan, Premanand Christensen, Mikkel Coulson, Richard M. R. Todd, John A. T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research |
title | T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research |
title_full | T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research |
title_fullStr | T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research |
title_full_unstemmed | T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research |
title_short | T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research |
title_sort | t1dbase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013780/ https://www.ncbi.nlm.nih.gov/pubmed/20937630 http://dx.doi.org/10.1093/nar/gkq912 |
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