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T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research

T1DBase (http://www.t1dbase.org) is web platform, which supports the type 1 diabetes (T1D) community. It integrates genetic, genomic and expression data relevant to T1D research across mouse, rat and human and presents this to the user as a set of web pages and tools. This update describes the incor...

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Detalles Bibliográficos
Autores principales: Burren, Oliver S., Adlem, Ellen C., Achuthan, Premanand, Christensen, Mikkel, Coulson, Richard M. R., Todd, John A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013780/
https://www.ncbi.nlm.nih.gov/pubmed/20937630
http://dx.doi.org/10.1093/nar/gkq912
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author Burren, Oliver S.
Adlem, Ellen C.
Achuthan, Premanand
Christensen, Mikkel
Coulson, Richard M. R.
Todd, John A.
author_facet Burren, Oliver S.
Adlem, Ellen C.
Achuthan, Premanand
Christensen, Mikkel
Coulson, Richard M. R.
Todd, John A.
author_sort Burren, Oliver S.
collection PubMed
description T1DBase (http://www.t1dbase.org) is web platform, which supports the type 1 diabetes (T1D) community. It integrates genetic, genomic and expression data relevant to T1D research across mouse, rat and human and presents this to the user as a set of web pages and tools. This update describes the incorporation of new data sets, tools and curation efforts as well as a new website design to simplify site use. New data sets include curated summary data from four genome-wide association studies relevant to T1D, HaemAtlas—a data set and tool to query gene expression levels in haematopoietic cells and a manually curated table of human T1D susceptibility loci, incorporating genetic overlap with other related diseases. These developments will continue to support T1D research and allow easy access to large and complex T1D relevant data sets.
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spelling pubmed-30137802011-01-03 T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research Burren, Oliver S. Adlem, Ellen C. Achuthan, Premanand Christensen, Mikkel Coulson, Richard M. R. Todd, John A. Nucleic Acids Res Articles T1DBase (http://www.t1dbase.org) is web platform, which supports the type 1 diabetes (T1D) community. It integrates genetic, genomic and expression data relevant to T1D research across mouse, rat and human and presents this to the user as a set of web pages and tools. This update describes the incorporation of new data sets, tools and curation efforts as well as a new website design to simplify site use. New data sets include curated summary data from four genome-wide association studies relevant to T1D, HaemAtlas—a data set and tool to query gene expression levels in haematopoietic cells and a manually curated table of human T1D susceptibility loci, incorporating genetic overlap with other related diseases. These developments will continue to support T1D research and allow easy access to large and complex T1D relevant data sets. Oxford University Press 2011-01 2010-10-11 /pmc/articles/PMC3013780/ /pubmed/20937630 http://dx.doi.org/10.1093/nar/gkq912 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Burren, Oliver S.
Adlem, Ellen C.
Achuthan, Premanand
Christensen, Mikkel
Coulson, Richard M. R.
Todd, John A.
T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
title T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
title_full T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
title_fullStr T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
title_full_unstemmed T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
title_short T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
title_sort t1dbase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013780/
https://www.ncbi.nlm.nih.gov/pubmed/20937630
http://dx.doi.org/10.1093/nar/gkq912
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