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The Pancreatic Expression database: 2011 update

The Pancreatic Expression database (PED, http://www.pancreasexpression.org) has established itself as the main repository for pancreatic-derived -omics data. For the past 3 years, its data content and access have increased substantially. Here we describe several of its new and improved features, suc...

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Detalles Bibliográficos
Autores principales: Cutts, Rosalind J., Gadaleta, Emanuela, Hahn, Stephan A., Crnogorac-Jurcevic, Tatjana, Lemoine, Nicholas R., Chelala, Claude
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013788/
https://www.ncbi.nlm.nih.gov/pubmed/20959292
http://dx.doi.org/10.1093/nar/gkq937
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author Cutts, Rosalind J.
Gadaleta, Emanuela
Hahn, Stephan A.
Crnogorac-Jurcevic, Tatjana
Lemoine, Nicholas R.
Chelala, Claude
author_facet Cutts, Rosalind J.
Gadaleta, Emanuela
Hahn, Stephan A.
Crnogorac-Jurcevic, Tatjana
Lemoine, Nicholas R.
Chelala, Claude
author_sort Cutts, Rosalind J.
collection PubMed
description The Pancreatic Expression database (PED, http://www.pancreasexpression.org) has established itself as the main repository for pancreatic-derived -omics data. For the past 3 years, its data content and access have increased substantially. Here we describe several of its new and improved features, such as data content, which now includes over 60 000 measurements derived from transcriptomics, proteomics, genomics and miRNA profiles from various pancreas-centred reports on a broad range of specimen and experimental types. We also illustrate the capabilities of its interface, which allows integrative queries that can combine PED data with a growing number of biological resources such as NCBI, Ensembl, UniProt and Reactome. Thus, PED is capable of retrieving and integrating different types of -omics, annotations and clinical data. We also focus on the importance of data sharing and interoperability in the cancer field, and the integration of PED into the International Cancer Genome Consortium (ICGC) data portal.
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spelling pubmed-30137882011-01-03 The Pancreatic Expression database: 2011 update Cutts, Rosalind J. Gadaleta, Emanuela Hahn, Stephan A. Crnogorac-Jurcevic, Tatjana Lemoine, Nicholas R. Chelala, Claude Nucleic Acids Res Articles The Pancreatic Expression database (PED, http://www.pancreasexpression.org) has established itself as the main repository for pancreatic-derived -omics data. For the past 3 years, its data content and access have increased substantially. Here we describe several of its new and improved features, such as data content, which now includes over 60 000 measurements derived from transcriptomics, proteomics, genomics and miRNA profiles from various pancreas-centred reports on a broad range of specimen and experimental types. We also illustrate the capabilities of its interface, which allows integrative queries that can combine PED data with a growing number of biological resources such as NCBI, Ensembl, UniProt and Reactome. Thus, PED is capable of retrieving and integrating different types of -omics, annotations and clinical data. We also focus on the importance of data sharing and interoperability in the cancer field, and the integration of PED into the International Cancer Genome Consortium (ICGC) data portal. Oxford University Press 2011-01 2010-10-18 /pmc/articles/PMC3013788/ /pubmed/20959292 http://dx.doi.org/10.1093/nar/gkq937 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Cutts, Rosalind J.
Gadaleta, Emanuela
Hahn, Stephan A.
Crnogorac-Jurcevic, Tatjana
Lemoine, Nicholas R.
Chelala, Claude
The Pancreatic Expression database: 2011 update
title The Pancreatic Expression database: 2011 update
title_full The Pancreatic Expression database: 2011 update
title_fullStr The Pancreatic Expression database: 2011 update
title_full_unstemmed The Pancreatic Expression database: 2011 update
title_short The Pancreatic Expression database: 2011 update
title_sort pancreatic expression database: 2011 update
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013788/
https://www.ncbi.nlm.nih.gov/pubmed/20959292
http://dx.doi.org/10.1093/nar/gkq937
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