Reduced Expression of the ROCK Inhibitor Rnd3 Is Associated with Increased Invasiveness and Metastatic Potential in Mesenchymal Tumor Cells

BACKGROUND: Mesenchymal and amoeboid movements are two important mechanisms adopted by cancer cells to invade the surrounding environment. Mesenchymal movement depends on extracellular matrix protease activity, amoeboid movement on the RhoA-dependent kinase ROCK. Cancer cells can switch from one mec...

Descripción completa

Detalles Bibliográficos
Autores principales: Belgiovine, Cristina, Frapolli, Roberta, Bonezzi, Katiuscia, Chiodi, Ilaria, Favero, Francesco, Mello-Grand, Maurizia, Dei Tos, Angelo P., Giulotto, Elena, Taraboletti, Giulia, D'Incalci, Maurizio, Mondello, Chiara
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014295/
https://www.ncbi.nlm.nih.gov/pubmed/21209796
http://dx.doi.org/10.1371/journal.pone.0014154

Ejemplares similares

Ejemplares similares