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Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity
Tie-2 is a member of the receptor tyrosine kinase family and is required for vascular remodeling and maintenance of mammalian vessel integrity. A number of mutations in the human TIE2 gene have been identified in patients suffering from cutaneomucosal venous malformations and ventricular septal defe...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Limited
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014345/ https://www.ncbi.nlm.nih.gov/pubmed/21045210 http://dx.doi.org/10.1242/dmm.005033 |