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Pseudokinases-remnants of evolution or key allosteric regulators?

Protein kinases provide a platform for the integration of signal transduction networks. A key feature of transmitting these cellular signals is the ability of protein kinases to activate one another by phosphorylation. A number of kinases are predicted by sequence homology to be incapable of phospho...

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Detalles Bibliográficos
Autores principales: Zeqiraj, Elton, van Aalten, Daan MF
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014569/
https://www.ncbi.nlm.nih.gov/pubmed/21074407
http://dx.doi.org/10.1016/j.sbi.2010.10.001