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Pseudosarcomatous Proliferation of Cx43- and Kit-Expressing Interstitial Cell in the Urinary Bladder
The authors report a case showing proliferation of KIT- and connexin 43-expressing mesenchymal cells of the urinary bladder. A 75-year-old woman had an ulcerated endophytic mass (size, approximately 2 × 2 cm) in the left posterolateral wall. She underwent transurethral resection and subsequent parti...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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SAGE-Hindawi Access to Research
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014713/ https://www.ncbi.nlm.nih.gov/pubmed/21234420 http://dx.doi.org/10.4061/2010/961325 |
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author | Takeuchi, Tamotsu Tanimura, Masanobu Shimamoto, Tsutomu Yasuda, Masaharu Furihata, Mutsuo |
author_facet | Takeuchi, Tamotsu Tanimura, Masanobu Shimamoto, Tsutomu Yasuda, Masaharu Furihata, Mutsuo |
author_sort | Takeuchi, Tamotsu |
collection | PubMed |
description | The authors report a case showing proliferation of KIT- and connexin 43-expressing mesenchymal cells of the urinary bladder. A 75-year-old woman had an ulcerated endophytic mass (size, approximately 2 × 2 cm) in the left posterolateral wall. She underwent transurethral resection and subsequent partial cystectomy. The suburothelial mass extended to the muscularis propria. The histopathological analysis revealed spindle-shaped mesenchymal cells that were loosely arranged with myxoid stroma and showed a focal compact fascicular arrangement. In the immunohistochemical analysis, these spindle cells were stained with specific antibodies to KIT and connexin 43. The patient is currently free of disease at 5 years after operation. The proliferating spindle cells in the present case might represent a phenotype of interstitial cells of the lamina propria. |
format | Text |
id | pubmed-3014713 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | SAGE-Hindawi Access to Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-30147132011-01-13 Pseudosarcomatous Proliferation of Cx43- and Kit-Expressing Interstitial Cell in the Urinary Bladder Takeuchi, Tamotsu Tanimura, Masanobu Shimamoto, Tsutomu Yasuda, Masaharu Furihata, Mutsuo Patholog Res Int Case Report The authors report a case showing proliferation of KIT- and connexin 43-expressing mesenchymal cells of the urinary bladder. A 75-year-old woman had an ulcerated endophytic mass (size, approximately 2 × 2 cm) in the left posterolateral wall. She underwent transurethral resection and subsequent partial cystectomy. The suburothelial mass extended to the muscularis propria. The histopathological analysis revealed spindle-shaped mesenchymal cells that were loosely arranged with myxoid stroma and showed a focal compact fascicular arrangement. In the immunohistochemical analysis, these spindle cells were stained with specific antibodies to KIT and connexin 43. The patient is currently free of disease at 5 years after operation. The proliferating spindle cells in the present case might represent a phenotype of interstitial cells of the lamina propria. SAGE-Hindawi Access to Research 2010-12-22 /pmc/articles/PMC3014713/ /pubmed/21234420 http://dx.doi.org/10.4061/2010/961325 Text en Copyright © 2010 Tamotsu Takeuchi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Takeuchi, Tamotsu Tanimura, Masanobu Shimamoto, Tsutomu Yasuda, Masaharu Furihata, Mutsuo Pseudosarcomatous Proliferation of Cx43- and Kit-Expressing Interstitial Cell in the Urinary Bladder |
title | Pseudosarcomatous Proliferation of Cx43- and Kit-Expressing Interstitial Cell in the Urinary Bladder |
title_full | Pseudosarcomatous Proliferation of Cx43- and Kit-Expressing Interstitial Cell in the Urinary Bladder |
title_fullStr | Pseudosarcomatous Proliferation of Cx43- and Kit-Expressing Interstitial Cell in the Urinary Bladder |
title_full_unstemmed | Pseudosarcomatous Proliferation of Cx43- and Kit-Expressing Interstitial Cell in the Urinary Bladder |
title_short | Pseudosarcomatous Proliferation of Cx43- and Kit-Expressing Interstitial Cell in the Urinary Bladder |
title_sort | pseudosarcomatous proliferation of cx43- and kit-expressing interstitial cell in the urinary bladder |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014713/ https://www.ncbi.nlm.nih.gov/pubmed/21234420 http://dx.doi.org/10.4061/2010/961325 |
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