Increased mRNA Levels of TCF7L2 and MYC of the Wnt Pathway in Tg-ArcSwe Mice and Alzheimer's Disease Brain

Several components in the Wnt pathway, including β-catenin and glycogen synthase kinase 3 beta, have been implied in AD pathogenesis. Here, mRNA brain levels from five-month-old tg-ArcSwe and nontransgenic mice were compared using Affymetrix microarray analysis. With surprisingly small overall chang...

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Detalles Bibliográficos
Autores principales: Blom, Elin S., Wang, Yijing, Skoglund, Lena, Hansson, Anita C., Ubaldi, Massimo, Lourdusamy, Anbarasu, Sommer, Wolfgang H., Mielke, Matthew, Hyman, Bradley T., Heilig, Markus, Lannfelt, Lars, Nilsson, Lars N. G., Ingelsson, Martin
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014771/
https://www.ncbi.nlm.nih.gov/pubmed/21234373
http://dx.doi.org/10.4061/2011/936580

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