BALB/c Mice Deficient in CD4(+) T Cell IL-4Rα Expression Control Leishmania mexicana Load although Female but Not Male Mice Develop a Healer Phenotype

Immunologically intact BALB/c mice infected with Leishmania mexicana develop non-healing progressively growing lesions associated with a biased Th2 response while similarly infected IL-4Rα-deficient mice fail to develop lesions and develop a robust Th1 response. In order to determine the functional...

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Detalles Bibliográficos
Autores principales: Bryson, Karen J., Millington, Owain R., Mokgethi, Thabang, McGachy, H. Adrienne, Brombacher, Frank, Alexander, James
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014948/
https://www.ncbi.nlm.nih.gov/pubmed/21245915
http://dx.doi.org/10.1371/journal.pntd.0000930

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