DC-SIGN (CD209) Promoter −336 A/G Polymorphism Is Associated with Dengue Hemorrhagic Fever and Correlated to DC-SIGN Expression and Immune Augmentation

BACKGROUND: The C-type lectin DC-SIGN (CD209) is known to be the major dengue receptor on human dendritic cells, and a single nucleotide polymorphism (SNP) in the promoter region of CD209 (−336 A/G; rs4804803) is susceptible to many infectious diseases. We reason that variations in the DC-SIGN gene...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Chen, Rong-Fu, Liu, Jien-Wei, Lee, Ing-Kit, Lee, Chiu-Ping, Kuo, Ho-Chang, Huang, Shau-Ku, Yang, Kuender D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014977/
https://www.ncbi.nlm.nih.gov/pubmed/21245921
http://dx.doi.org/10.1371/journal.pntd.0000934

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