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De Novo Designed Proteins from a Library of Artificial Sequences Function in Escherichia Coli and Enable Cell Growth
A central challenge of synthetic biology is to enable the growth of living systems using parts that are not derived from nature, but designed and synthesized in the laboratory. As an initial step toward achieving this goal, we probed the ability of a collection of >10(6) de novo designed proteins...
Autores principales: | Fisher, Michael A., McKinley, Kara L., Bradley, Luke H., Viola, Sara R., Hecht, Michael H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014984/ https://www.ncbi.nlm.nih.gov/pubmed/21245923 http://dx.doi.org/10.1371/journal.pone.0015364 |
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