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Carbon Dioxide Embolism During Laparoscopy: Effect of Insufflation Pressure in Pigs
Carbon dioxide embolism is a rare but potentially devastating complication of laparoscopy. To determine the effects of insufflation pressure on the mortality from carbon dioxide embolism, six swine had intravascular insufflation with carbon dioxide for 30 seconds using a Karl Storz insufflator at a...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Society of Laparoendoscopic Surgeons
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3015330/ https://www.ncbi.nlm.nih.gov/pubmed/10444005 |
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author | Nagao, K. Reichert, J. Beebe, D.S. Fowler, J.M. Belani, K.G. |
author_facet | Nagao, K. Reichert, J. Beebe, D.S. Fowler, J.M. Belani, K.G. |
author_sort | Nagao, K. |
collection | PubMed |
description | Carbon dioxide embolism is a rare but potentially devastating complication of laparoscopy. To determine the effects of insufflation pressure on the mortality from carbon dioxide embolism, six swine had intravascular insufflation with carbon dioxide for 30 seconds using a Karl Storz insufflator at a flow rate of 35 mL/kg/min. The initial insufflation pressure was 15 mm Hg. Following recovery from the first embolism, intravascular insufflation using a pressure of 20 mm Hg at the same flow rate was performed in the surviving animals. Significantly less carbon dioxide (8.3 ± 2.7 versus 16.7 ± 3.9 ml/kg; p < 0.02) was insufflated intravascularly at 15 mm Hg than at 20 mm Hg pressure. All of the pigs insufflated at 15 mm Hg pressure with a flow rate of 35 mL/kg/min survived. In contrast, 4 of the 5 pigs insufflated at 20 mm Hg pressure died. The surviving pig died when insufflated with 25 mm Hg pressure following an embolism of 15.7 ml/kg. Intravascular injection was often associated with an initial rise in end-tidal carbon dioxide tension, followed by a rapid fall in all cases where the embolism proved fatal. Insufflation should be begun with a low pressure and a slow flow rate to limit the volume of gas embolized in the event of inadvertent venous cannulation. Insufflation should immediately be stopped if a sudden change in end-tidal carbon dioxide tension occurs. |
format | Text |
id | pubmed-3015330 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1999 |
publisher | Society of Laparoendoscopic Surgeons |
record_format | MEDLINE/PubMed |
spelling | pubmed-30153302011-02-17 Carbon Dioxide Embolism During Laparoscopy: Effect of Insufflation Pressure in Pigs Nagao, K. Reichert, J. Beebe, D.S. Fowler, J.M. Belani, K.G. JSLS Scientific Papers Carbon dioxide embolism is a rare but potentially devastating complication of laparoscopy. To determine the effects of insufflation pressure on the mortality from carbon dioxide embolism, six swine had intravascular insufflation with carbon dioxide for 30 seconds using a Karl Storz insufflator at a flow rate of 35 mL/kg/min. The initial insufflation pressure was 15 mm Hg. Following recovery from the first embolism, intravascular insufflation using a pressure of 20 mm Hg at the same flow rate was performed in the surviving animals. Significantly less carbon dioxide (8.3 ± 2.7 versus 16.7 ± 3.9 ml/kg; p < 0.02) was insufflated intravascularly at 15 mm Hg than at 20 mm Hg pressure. All of the pigs insufflated at 15 mm Hg pressure with a flow rate of 35 mL/kg/min survived. In contrast, 4 of the 5 pigs insufflated at 20 mm Hg pressure died. The surviving pig died when insufflated with 25 mm Hg pressure following an embolism of 15.7 ml/kg. Intravascular injection was often associated with an initial rise in end-tidal carbon dioxide tension, followed by a rapid fall in all cases where the embolism proved fatal. Insufflation should be begun with a low pressure and a slow flow rate to limit the volume of gas embolized in the event of inadvertent venous cannulation. Insufflation should immediately be stopped if a sudden change in end-tidal carbon dioxide tension occurs. Society of Laparoendoscopic Surgeons 1999 /pmc/articles/PMC3015330/ /pubmed/10444005 Text en © 1999 by JSLS, Journal of the Society of Laparoendoscopic Surgeons. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits for noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited and is not altered in any way. |
spellingShingle | Scientific Papers Nagao, K. Reichert, J. Beebe, D.S. Fowler, J.M. Belani, K.G. Carbon Dioxide Embolism During Laparoscopy: Effect of Insufflation Pressure in Pigs |
title | Carbon Dioxide Embolism During Laparoscopy: Effect of Insufflation Pressure in Pigs |
title_full | Carbon Dioxide Embolism During Laparoscopy: Effect of Insufflation Pressure in Pigs |
title_fullStr | Carbon Dioxide Embolism During Laparoscopy: Effect of Insufflation Pressure in Pigs |
title_full_unstemmed | Carbon Dioxide Embolism During Laparoscopy: Effect of Insufflation Pressure in Pigs |
title_short | Carbon Dioxide Embolism During Laparoscopy: Effect of Insufflation Pressure in Pigs |
title_sort | carbon dioxide embolism during laparoscopy: effect of insufflation pressure in pigs |
topic | Scientific Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3015330/ https://www.ncbi.nlm.nih.gov/pubmed/10444005 |
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