Cargando…

Genetic variants in the KIF6 region and coronary event reduction from statin therapy

A single nucleotide polymorphism (SNP) in KIF6, a member of the KIF9 family of kinesins, is associated with differential coronary event reduction from statin therapy in four randomized controlled trials; this SNP (rs20455) is also associated with the risk for coronary heart disease (CHD) in multiple...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yonghong, Sabatine, Marc S., Tong, Carmen H., Ford, Ian, Kirchgessner, Todd G., Packard, Christopher J., Robertson, Michele, Rowland, Charles M., Bare, Lance A., Shepherd, James, Devlin, James J., Iakoubova, Olga A.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016221/ https://www.ncbi.nlm.nih.gov/pubmed/20886236 http://dx.doi.org/10.1007/s00439-010-0892-6

Ejemplares similares

Assessment of the Association of Vitamin D Level With SARS-CoV-2 Seropositivity Among Working-Age Adults
por: Li, Yonghong, et al.
Publicado: (2021)

Genome-Wide Study of Gene Variants Associated with Differential Cardiovascular Event Reduction by Pravastatin Therapy
por: Shiffman, Dov, et al.
Publicado: (2012)

Investigation of KIF6 Trp719Arg in a Case-Control Study of Myocardial Infarction: A Costa Rican Population
por: Bare, Lance A., et al.
Publicado: (2010)

Workplace Outreach Program Improves Management of Chronic Kidney Disease
por: Iakoubova, Olga A., et al.
Publicado: (2022)

Association of changes in lipid levels with changes in vitamin D levels in a real-world setting
por: Li, Yonghong, et al.
Publicado: (2021)

High-Sensitivity Cardiac Troponin, Statin Therapy, and Risk of Coronary Heart Disease
por: Ford, Ian, et al.
Publicado: (2016)

Use of low density lipoprotein particle number levels as an aid in statin treatment decisions for intermediate risk patients: a cost-effectiveness analysis
por: Shiffman, Dov, et al.
Publicado: (2016)

Statin Discontinuation and Cardiovascular Events Among Older People in Denmark
por: Thompson, Wade, et al.
Publicado: (2021)

Cost Effectiveness of Sequencing 34 Cancer-Associated Genes as an Aid for Treatment Selection in Patients with Metastatic Melanoma
por: Li, Yonghong, et al.
Publicado: (2015)

Concordance of Cardiovascular Risk Factors and Behaviors in a Multiethnic US Nationwide Cohort of Married Couples and Domestic Partners
por: Shiffman, Dov, et al.
Publicado: (2020)

Protocol for analyses of adverse event data from randomized controlled trials of statin therapy
Publicado: (2016)

Relative contributions of statin intensity, achieved low-density lipoprotein cholesterol level, and statin therapy duration to cardiovascular risk reduction in patients with type 2 diabetes: population based cohort study
por: Kim, Ji Yoon, et al.
Publicado: (2022)

KIF6 gene as a pharmacogenetic marker for lipid-lowering effect in statin treatment
por: Ruiz-Iruela, Cristina, et al.
Publicado: (2018)

Reduced oxidized LDL in T2D plaques is associated with a greater statin usage but not with future cardiovascular events
por: Singh, Pratibha, et al.
Publicado: (2020)

Patient Preference Distribution for Use of Statin Therapy
por: Brodney, Suzanne, et al.
Publicado: (2021)

Comparative Mapping Between Coho Salmon (Oncorhynchus kisutch) and Three Other Salmonids Suggests a Role for Chromosomal Rearrangements in the Retention of Duplicated Regions Following a Whole Genome Duplication Event
por: Kodama, Miyako, et al.
Publicado: (2014)

The contribution of a 9p21.3 variant, a KIF6 variant, and C-reactive protein to predicting risk of myocardial infarction in a prospective study
por: Shiffman, Dov, et al.
Publicado: (2011)

Effect of sarpogrelate and high‐dose statin on the reduction of coronary spasm in vasospastic angina: A two by two factorial, pilot randomized study
por: Kim, So Ree, et al.
Publicado: (2019)

Side Effect Patterns in a Crossover Trial of Statin, Placebo, and No Treatment
por: Howard, James P., et al.
Publicado: (2021)

Trends in Use and Expenditures for Brand-name Statins After Introduction of Generic Statins in the US, 2002-2018
por: Lin, Shuo-yu, et al.
Publicado: (2021)

Should all patients with psoriasis receive statins? Analysis according to different strategies()()
por: Masson, Walter, et al.
Publicado: (2019)

Atherosclerotic Cardiovascular Disease Events in Adults With CKD Taking a Moderate- or High-Intensity Statin: The Chronic Renal Insufficiency Cohort (CRIC) Study
por: Poudel, Bharat, et al.
Publicado: (2021)

Meta-Analyses of KIF6 Trp719Arg in Coronary Heart Disease and Statin Therapeutic Effect
por: Peng, Ping, et al.
Publicado: (2012)

Analysis of Human Performance Deficiencies Associated With Surgical Adverse Events
por: Suliburk, James W., et al.
Publicado: (2019)

Genetic risk for atrial fibrillation could motivate patient adherence to warfarin therapy: a cost effectiveness analysis
por: Shiffman, Dov, et al.
Publicado: (2015)

Association of Familial Hypercholesterolemia and Statin Use With Risk of Dementia in Norway
por: Mundal, Liv J., et al.
Publicado: (2022)

Association of Statin Use With Risk of Liver Disease, Hepatocellular Carcinoma, and Liver-Related Mortality
por: Vell, Mara Sophie, et al.
Publicado: (2023)

Association Between Intensity of Low-Density Lipoprotein Cholesterol Reduction With Statin-Based Therapies and Secondary Stroke Prevention: A Meta-analysis of Randomized Clinical Trials
por: Lee, Meng, et al.
Publicado: (2022)

Long-term impact on healthcare resource utilization of statin treatment, and its cost effectiveness in the primary prevention of cardiovascular disease: a record linkage study
por: McConnachie, Alex, et al.
Publicado: (2014)

An interphase pool of KIF11 localizes at the basal bodies of primary cilia and a reduction in KIF11 expression alters cilia dynamics
por: Zalenski, Abigail A., et al.
Publicado: (2020)

KIF6 p.Trp719Arg Testing to Assess Risk of Coronary Artery Disease and/or Statin Response
por: Allingham-Hawkins, Diane, et al.
Publicado: (2010)

Haemostasis, inflammation and renal function following exercise in patients with intermittent claudication on statin and aspirin therapy
por: Collins, Patrick, et al.
Publicado: (2006)

Statin Use, Cholesterol Level, and Mortality Among Females With Breast Cancer
por: Murto, Mika O., et al.
Publicado: (2023)

Perinatal Outcomes After Statin Exposure During Pregnancy
por: Chang, Jui-Chun, et al.
Publicado: (2021)

Effects of background statin therapy on glycemic response and cardiovascular events following initiation of insulin therapy in type 2 diabetes: a large UK cohort study
por: Anyanwagu, Uchenna, et al.
Publicado: (2017)

Genome Wide Epistasis Study of On-Statin Cardiovascular Events with Iterative Feature Reduction and Selection
por: Adams, Solomon M., et al.
Publicado: (2020)

Long-Term Safety and Efficacy of Lowering Low-Density Lipoprotein Cholesterol With Statin Therapy: 20-Year Follow-Up of West of Scotland Coronary Prevention Study
por: Ford, Ian, et al.
Publicado: (2016)

Patterns and predictors of statin prescription in patients with type 2 diabetes
por: Berthold, Heiner K, et al.
Publicado: (2009)

Prescribing of Statins After Lower Extremity Revascularization Procedures in the US
por: Singh, Nikhil, et al.
Publicado: (2021)

Association Between Statin Use at the Time of Intra-abdominal Surgery and Postoperative Adhesion-Related Complications and Small-Bowel Obstruction
por: Scott, Frank I., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1203ttdeuv7eii293vdg5i8jlf