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Cloud computing and validation of expandable in silico livers

BACKGROUND: In Silico Livers (ISLs) are works in progress. They are used to challenge multilevel, multi-attribute, mechanistic hypotheses about the hepatic disposition of xenobiotics coupled with hepatic responses. To enhance ISL-to-liver mappings, we added discrete time metabolism, biliary eliminat...

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Detalles Bibliográficos
Autores principales: Ropella, Glen EP, Hunt, C Anthony
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016276/
https://www.ncbi.nlm.nih.gov/pubmed/21129207
http://dx.doi.org/10.1186/1752-0509-4-168