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Cloud computing and validation of expandable in silico livers
BACKGROUND: In Silico Livers (ISLs) are works in progress. They are used to challenge multilevel, multi-attribute, mechanistic hypotheses about the hepatic disposition of xenobiotics coupled with hepatic responses. To enhance ISL-to-liver mappings, we added discrete time metabolism, biliary eliminat...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016276/ https://www.ncbi.nlm.nih.gov/pubmed/21129207 http://dx.doi.org/10.1186/1752-0509-4-168 |