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Effect modification of air pollution on Urinary 8-Hydroxy-2'-Deoxyguanosine by genotypes: an application of the multiple testing procedure to identify significant SNP interactions

BACKGROUND: Air pollution is associated with adverse human health, but mechanisms through which pollution exerts effects remain to be clarified. One suggested pathway is that pollution causes oxidative stress. If so, oxidative stress-related genotypes may modify the oxidative response defenses to po...

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Detalles Bibliográficos
Autores principales: Ren, Cizao, Vokonas, Pantel S, Suh, Helen, Fang, Shona, Christiani, David C, Schwartz, Joel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016327/
https://www.ncbi.nlm.nih.gov/pubmed/21138591
http://dx.doi.org/10.1186/1476-069X-9-78