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Potentiation of excitatory transmission in substantia gelatinosa neurons of rat spinal cord by inhibition of estrogen receptor alpha

BACKGROUND: It has been shown that estrogen is synthesized in the spinal dorsal horn and plays a role in modulating pain transmission. One of the estrogen receptor (ER) subtypes, estrogen receptor alpha (ERα), is expressed in the spinal laminae I-V, including substantia gelatinosa (SG, lamina II). H...

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Detalles Bibliográficos
Autores principales: Zhong, Yan-Qing, Li, Kai-Cheng, Zhang, Xu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016347/
https://www.ncbi.nlm.nih.gov/pubmed/21143988
http://dx.doi.org/10.1186/1744-8069-6-92

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