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Heparan Sulfate Proteoglycans Mediate Interstitial Flow Mechanotransduction Regulating MMP-13 Expression and Cell Motility via FAK-ERK in 3D Collagen

BACKGROUND: Interstitial flow directly affects cells that reside in tissues and regulates tissue physiology and pathology by modulating important cellular processes including proliferation, differentiation, and migration. However, the structures that cells utilize to sense interstitial flow in a 3-d...

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Detalles Bibliográficos
Autores principales:	Shi, Zhong-Dong, Wang, Hui, Tarbell, John M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016412/ https://www.ncbi.nlm.nih.gov/pubmed/21246051 http://dx.doi.org/10.1371/journal.pone.0015956

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