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Irreversible AE1 Tyrosine Phosphorylation Leads to Membrane Vesiculation in G6PD Deficient Red Cells

BACKGROUND: While G6PD deficiency is one of the major causes of acute hemolytic anemia, the membrane changes leading to red cell lysis have not been extensively studied. New findings concerning the mechanisms of G6PD deficient red cell destruction may facilitate our understanding of the large indivi...

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Detalles Bibliográficos
Autores principales: Pantaleo, Antonella, Ferru, Emanuela, Carta, Franco, Mannu, Franca, Simula, Luigi F., Khadjavi, Amina, Pippia, Proto, Turrini, Francesco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016414/
https://www.ncbi.nlm.nih.gov/pubmed/21246053
http://dx.doi.org/10.1371/journal.pone.0015847