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PoolHap: Inferring Haplotype Frequencies from Pooled Samples by Next Generation Sequencing
With the advance of next-generation sequencing (NGS) technologies, increasingly ambitious applications are becoming feasible. A particularly powerful one is the sequencing of polymorphic, pooled samples. The pool can be naturally occurring, as in the case of multiple pathogen strains in a blood samp...
Autores principales: | Long, Quan, Jeffares, Daniel C., Zhang, Qingrun, Ye, Kai, Nizhynska, Viktoria, Ning, Zemin, Tyler-Smith, Chris, Nordborg, Magnus |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016441/ https://www.ncbi.nlm.nih.gov/pubmed/21264334 http://dx.doi.org/10.1371/journal.pone.0015292 |
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