Cargando…
A study evaluating the safety of laparoscopic radical operation for colorectal cancer
AIM: This study aimed to assess the safety and feasibility of laparoscopic curative resection for colorectal cancer through the clinical practice and basic research. MATERIAL AND METHODS: From September 2001 to September 2002, 47 patients with colorectal cancer were treated using laparoscopic approa...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016472/ https://www.ncbi.nlm.nih.gov/pubmed/21234141 http://dx.doi.org/10.4103/0972-9941.15243 |
_version_ | 1782195751146749952 |
---|---|
author | Zheng, Min-Hua Lu, Ai-Guo Feng, Bo Hu, Yan-Yan Li, Jian-Wen Wang, Ming-Liang Dong, Feng Cai, Jing-Li Jiang, Yu |
author_facet | Zheng, Min-Hua Lu, Ai-Guo Feng, Bo Hu, Yan-Yan Li, Jian-Wen Wang, Ming-Liang Dong, Feng Cai, Jing-Li Jiang, Yu |
author_sort | Zheng, Min-Hua |
collection | PubMed |
description | AIM: This study aimed to assess the safety and feasibility of laparoscopic curative resection for colorectal cancer through the clinical practice and basic research. MATERIAL AND METHODS: From September 2001 to September 2002, 47 patients with colorectal cancer were treated using laparoscopic approach, compared with 113 patients underwent traditional operation. The length of intestinal segment excised, size of tumour, clearance of lymph nodes, local recurrence and distant metastasis rate during the period of follow-up in both groups were compared. The other part of the study involved the detection of exfoliated tumour cells in the peritoneal washing before and after surgery; flushing of the instruments was performed in both groups and the results compared. For the laparoscopic cases, the filtrated liquid of CO(2) pneumoperitoneum was also checked for tumour cells. RESULTS: No significant differences existed in tumour size, operative site and manner between the two groups. The exfoliated tumour cell was not detected in the CO(2) filtrated liquid. Between both groups there was no difference in the incidence of exfoliated tumour cells in peritoneal washing before and after surgery as well as in the fluid used for flushing the instruments. The total number of lymph nodes harvested was 13.71±9.57 for the laparoscopic group and 12.10±9.74 for the traditional procedure. Similar length of colon was excised in both groups; this was (19.38±7.47) cm in the laparoscopic and (18.60±8.40) cm in the traditional groups. The distal margins of resection for rectal cancer were (4.19±2.52) cm and (4.16±2.00) cm respectively. The local recurrence rate was 2.13% (1/47) and 1.77% (2/113) with the distant metastasis rate 6.38% (3/47) and 6.19% (7/113) respectively. Both the statistics were comparable between the laparoscopic and traditional surgery for the colorectal cancer. CONCLUSION: Laparoscopic curative resection for colorectal cancer can be performed safely and effectively. In the treatment of colorectal malignancy, laparoscopic resection can achieve similar radicalilty as compared to the traditional laparotomy. |
format | Text |
id | pubmed-3016472 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-30164722011-01-13 A study evaluating the safety of laparoscopic radical operation for colorectal cancer Zheng, Min-Hua Lu, Ai-Guo Feng, Bo Hu, Yan-Yan Li, Jian-Wen Wang, Ming-Liang Dong, Feng Cai, Jing-Li Jiang, Yu J Minim Access Surg Original Article AIM: This study aimed to assess the safety and feasibility of laparoscopic curative resection for colorectal cancer through the clinical practice and basic research. MATERIAL AND METHODS: From September 2001 to September 2002, 47 patients with colorectal cancer were treated using laparoscopic approach, compared with 113 patients underwent traditional operation. The length of intestinal segment excised, size of tumour, clearance of lymph nodes, local recurrence and distant metastasis rate during the period of follow-up in both groups were compared. The other part of the study involved the detection of exfoliated tumour cells in the peritoneal washing before and after surgery; flushing of the instruments was performed in both groups and the results compared. For the laparoscopic cases, the filtrated liquid of CO(2) pneumoperitoneum was also checked for tumour cells. RESULTS: No significant differences existed in tumour size, operative site and manner between the two groups. The exfoliated tumour cell was not detected in the CO(2) filtrated liquid. Between both groups there was no difference in the incidence of exfoliated tumour cells in peritoneal washing before and after surgery as well as in the fluid used for flushing the instruments. The total number of lymph nodes harvested was 13.71±9.57 for the laparoscopic group and 12.10±9.74 for the traditional procedure. Similar length of colon was excised in both groups; this was (19.38±7.47) cm in the laparoscopic and (18.60±8.40) cm in the traditional groups. The distal margins of resection for rectal cancer were (4.19±2.52) cm and (4.16±2.00) cm respectively. The local recurrence rate was 2.13% (1/47) and 1.77% (2/113) with the distant metastasis rate 6.38% (3/47) and 6.19% (7/113) respectively. Both the statistics were comparable between the laparoscopic and traditional surgery for the colorectal cancer. CONCLUSION: Laparoscopic curative resection for colorectal cancer can be performed safely and effectively. In the treatment of colorectal malignancy, laparoscopic resection can achieve similar radicalilty as compared to the traditional laparotomy. Medknow Publications 2005-03 /pmc/articles/PMC3016472/ /pubmed/21234141 http://dx.doi.org/10.4103/0972-9941.15243 Text en © Journal of Minimal Access Surgery http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Zheng, Min-Hua Lu, Ai-Guo Feng, Bo Hu, Yan-Yan Li, Jian-Wen Wang, Ming-Liang Dong, Feng Cai, Jing-Li Jiang, Yu A study evaluating the safety of laparoscopic radical operation for colorectal cancer |
title | A study evaluating the safety of laparoscopic radical operation for colorectal cancer |
title_full | A study evaluating the safety of laparoscopic radical operation for colorectal cancer |
title_fullStr | A study evaluating the safety of laparoscopic radical operation for colorectal cancer |
title_full_unstemmed | A study evaluating the safety of laparoscopic radical operation for colorectal cancer |
title_short | A study evaluating the safety of laparoscopic radical operation for colorectal cancer |
title_sort | study evaluating the safety of laparoscopic radical operation for colorectal cancer |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016472/ https://www.ncbi.nlm.nih.gov/pubmed/21234141 http://dx.doi.org/10.4103/0972-9941.15243 |
work_keys_str_mv | AT zhengminhua astudyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT luaiguo astudyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT fengbo astudyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT huyanyan astudyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT lijianwen astudyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT wangmingliang astudyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT dongfeng astudyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT caijingli astudyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT jiangyu astudyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT zhengminhua studyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT luaiguo studyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT fengbo studyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT huyanyan studyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT lijianwen studyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT wangmingliang studyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT dongfeng studyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT caijingli studyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer AT jiangyu studyevaluatingthesafetyoflaparoscopicradicaloperationforcolorectalcancer |