Fluoroquinolone and Macrolide Treatment Failure in Pneumococcal Pneumonia and Selection of Multidrug-Resistant Isolates

Streptococcus pneumoniae serotype 3, isolated from a penicillin-allergic patient and initially susceptible to fluoroquinolones, macrolides, lincosamides, quinupristin-dalfopristin, and telithromycin, became resistant to all these drugs during treatment. Mutations in the parC and gyrA and in the 23S...

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Autores principales: Pérez-Trallero, Emilio, Marimon, José M., Iglesias, Luis, Larruskain, Julián
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2003
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016791/
https://www.ncbi.nlm.nih.gov/pubmed/14519256
http://dx.doi.org/10.3201/eid0909.020810
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author Pérez-Trallero, Emilio
Marimon, José M.
Iglesias, Luis
Larruskain, Julián
author_facet Pérez-Trallero, Emilio
Marimon, José M.
Iglesias, Luis
Larruskain, Julián
author_sort Pérez-Trallero, Emilio
collection PubMed
description Streptococcus pneumoniae serotype 3, isolated from a penicillin-allergic patient and initially susceptible to fluoroquinolones, macrolides, lincosamides, quinupristin-dalfopristin, and telithromycin, became resistant to all these drugs during treatment. Mutations in the parC and gyrA and in the 23S rRNA and the ribosomal protein L22 genes were detected in the resistant isolates.
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spelling pubmed-30167912011-01-20 Fluoroquinolone and Macrolide Treatment Failure in Pneumococcal Pneumonia and Selection of Multidrug-Resistant Isolates Pérez-Trallero, Emilio Marimon, José M. Iglesias, Luis Larruskain, Julián Emerg Infect Dis Dispatch Streptococcus pneumoniae serotype 3, isolated from a penicillin-allergic patient and initially susceptible to fluoroquinolones, macrolides, lincosamides, quinupristin-dalfopristin, and telithromycin, became resistant to all these drugs during treatment. Mutations in the parC and gyrA and in the 23S rRNA and the ribosomal protein L22 genes were detected in the resistant isolates. Centers for Disease Control and Prevention 2003-09 /pmc/articles/PMC3016791/ /pubmed/14519256 http://dx.doi.org/10.3201/eid0909.020810 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Pérez-Trallero, Emilio
Marimon, José M.
Iglesias, Luis
Larruskain, Julián
Fluoroquinolone and Macrolide Treatment Failure in Pneumococcal Pneumonia and Selection of Multidrug-Resistant Isolates
title Fluoroquinolone and Macrolide Treatment Failure in Pneumococcal Pneumonia and Selection of Multidrug-Resistant Isolates
title_full Fluoroquinolone and Macrolide Treatment Failure in Pneumococcal Pneumonia and Selection of Multidrug-Resistant Isolates
title_fullStr Fluoroquinolone and Macrolide Treatment Failure in Pneumococcal Pneumonia and Selection of Multidrug-Resistant Isolates
title_full_unstemmed Fluoroquinolone and Macrolide Treatment Failure in Pneumococcal Pneumonia and Selection of Multidrug-Resistant Isolates
title_short Fluoroquinolone and Macrolide Treatment Failure in Pneumococcal Pneumonia and Selection of Multidrug-Resistant Isolates
title_sort fluoroquinolone and macrolide treatment failure in pneumococcal pneumonia and selection of multidrug-resistant isolates
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016791/
https://www.ncbi.nlm.nih.gov/pubmed/14519256
http://dx.doi.org/10.3201/eid0909.020810
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