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Patan hospital experience in treating philadelphia chromosome/BCR-ABL1 positive chronic myeloid leukemia patients with gleevec (imatinib mesylate); the first generation specific tyrosine kinase inhibitor

BACKGROUND: Chronic Myeloid Leukemia (CML) is caused by the abnormal fusion protein BCR-ABL1, a constitutively active tyrosine kinase and product of the Philadelphia chromosome. Gleevec (Imatinib mesylate) is a selective inhibitor of this kinase. Treatment with this agent is known to result in hemat...

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Detalles Bibliográficos
Autores principales:	Kayastha, Gyan K, Gurung, Padma, Acharya, Paras K, Paudyal, Buddhi P, Hayes, Bruce, Zimmerman, Mark, Karki, Arjun, Mansfield, Aaron S
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017013/ https://www.ncbi.nlm.nih.gov/pubmed/21138592 http://dx.doi.org/10.1186/1471-2326-10-8

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