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Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data

One of the biggest obstacles to progress in modern pharmaceutical research is the difficulty of integrating all available research findings into effective therapies for humans. Studies of traditionally used pharmacologically active plants and other substances in traditional medicines may be valuable...

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Detalles Bibliográficos
Autores principales: Samwald, Matthias, Dumontier, Michel, Zhao, Jun, Luciano, Joanne S, Marshall, Michael Scott, Cheung, Kei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017053/
https://www.ncbi.nlm.nih.gov/pubmed/21167050
http://dx.doi.org/10.1186/1749-8546-5-43
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author Samwald, Matthias
Dumontier, Michel
Zhao, Jun
Luciano, Joanne S
Marshall, Michael Scott
Cheung, Kei
author_facet Samwald, Matthias
Dumontier, Michel
Zhao, Jun
Luciano, Joanne S
Marshall, Michael Scott
Cheung, Kei
author_sort Samwald, Matthias
collection PubMed
description One of the biggest obstacles to progress in modern pharmaceutical research is the difficulty of integrating all available research findings into effective therapies for humans. Studies of traditionally used pharmacologically active plants and other substances in traditional medicines may be valuable sources of previously unknown compounds with therapeutic actions. However, the integration of findings from traditional medicines can be fraught with difficulties and misunderstandings. This article proposes an approach to use linked open data and Semantic Web technologies to address the heterogeneous data integration problem. The approach is based on our initial experiences with implementing an integrated web of data for a selected use-case, i.e., the identification of plant species used in Chinese medicine that indicate potential antidepressant activities.
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spelling pubmed-30170532011-01-07 Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data Samwald, Matthias Dumontier, Michel Zhao, Jun Luciano, Joanne S Marshall, Michael Scott Cheung, Kei Chin Med Commentary One of the biggest obstacles to progress in modern pharmaceutical research is the difficulty of integrating all available research findings into effective therapies for humans. Studies of traditionally used pharmacologically active plants and other substances in traditional medicines may be valuable sources of previously unknown compounds with therapeutic actions. However, the integration of findings from traditional medicines can be fraught with difficulties and misunderstandings. This article proposes an approach to use linked open data and Semantic Web technologies to address the heterogeneous data integration problem. The approach is based on our initial experiences with implementing an integrated web of data for a selected use-case, i.e., the identification of plant species used in Chinese medicine that indicate potential antidepressant activities. BioMed Central 2010-12-17 /pmc/articles/PMC3017053/ /pubmed/21167050 http://dx.doi.org/10.1186/1749-8546-5-43 Text en Copyright ©2010 Samwald et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<url>http://creativecommons.org/licenses/by/2.0</url>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Samwald, Matthias
Dumontier, Michel
Zhao, Jun
Luciano, Joanne S
Marshall, Michael Scott
Cheung, Kei
Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data
title Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data
title_full Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data
title_fullStr Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data
title_full_unstemmed Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data
title_short Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data
title_sort integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017053/
https://www.ncbi.nlm.nih.gov/pubmed/21167050
http://dx.doi.org/10.1186/1749-8546-5-43
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